Oxidative stress plays a major part in the development of chronic and degenerative diseases such as cancer, arthritis, aging, autoimmune disorders, cardiovascular and neurodegenerative diseases. Free radicals are generated from immune cell activation, inflammation, mental stress, excessive exercise, ischemia, infection, cancer and aging. They also result from air and water pollution, cigarette smoking, alcohol, heavy metals, certain drugs, industrial solvents, cooking and radiation